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101 Citations
- Katherine D. Travnicek
- 2019
Medicine
Deer's Treatment of Pain
Most guidelines and current evidence support short-term use for all medications discussed in this chapter, and there is no clear evidence to show superiority of one muscle relaxant over another in managing acute low back pain.
- Emmanuel M. Knight
- 2022
Medicine
Journal of the American Geriatrics Society
Questions often arise about whether the choice of muscle relaxant matters in older patients; or if there are potentially safer options available that do not contain strong recommendations to avoid use from the AGS Beers Criteria, available literature, or drug references.
- PDF
- Lívia Helena Freitas da Silva CascaesJardel Corrêa de Oliveira
- 2018
Medicine
Muscle relaxants in general compared to placebo or to each other showed little evidence with significant statistics, therefore the drug selection should be based on the profile of adverse effects, patient preference, potential of abuse, Potential of interaction with other drugs, cost and other characteristics of the drugs.
- Ling-ling ZhuYan-hong WangQuan Zhou
- 2024
Medicine
Journal of pain research
Tizanidine is an SMR with unique features and may be an optimal initial choice for older adults and there would be more scientific studies, wider therapeutic applications, and new drug formulations in the future.
- Highly Influenced[PDF]
- C. A. ShaheedChristopher G. MaherC. MaherKylie A. WilliamsA. McLachlanA. McLachlan
- 2017
Medicine
European journal of pain
Five trials provide high quality evidence that muscle relaxants provide clinically significant pain relief in the short term for acute LBP, and there was no eligible RCT evidence to support the efficacy of benzodiazepines in LBP.
- 80
- Hyun-Jung JungH. Chae
- 2019
Medicine
Methocarbamol has proven to be an effective and safe drug for use as a supplement to exercise regimen, physiotherapy and other activities to ease the discomfort associated with acute musculoskeletal disorders.
- D. MinaK. JohansenC. McCullochM. SteinmanB. GrimesJulie H. Ishida
- 2019
Medicine
American journal of kidney diseases : the…
Muscle relaxant use was common in hemodialysis patients and associated with altered mental status and falls and the lower risk for death with muscle relaxants may have been the result of residual confounding.
- 12
- Dermot P MaherB. ShahYakov Vorobeychik
- 2019
Medicine
Spine Pain Care
Although there is still insufficient evidence to recommend cannabinoids for spine pain treatment, this chapter discusses this emerging medication class because it has been already used to treat certain pain conditions.
- R. MattisonSarah MidkiffJustin P. ReinertMichael A. Veronin
- 2021
Medicine
Journal of perioperative practice
The objective of this review was to determine the efficacy and safety of adjunctive muscle relaxers for the purposes of analgesia in the perioperative setting.
- 2
- B. Mccarberg
- 2010
Medicine
Current medical research and opinion
A wide range of treatments is currently recommended for the management of patients with acute back pain and all are supported by results from controlled clinical trials, which support the view that both NSAIDs and low-level continuous heat treatment are more effective than acetaminophen.
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22 References
- R. ChouK. PetersonM. Helfand
- 2004
Medicine
Journal of pain and symptom management
- 276
- Highly Influential
- PDF
- Frank A. BeebeR. BarkinS. Barkin
- 2005
Medicine
American journal of therapeutics
Only a limited number of high-quality, randomized, controlled trials (RCTs) provide evidence of the effectiveness of NSAIDs or SMRs in the treatment of acute, uncomplicated MSDs, and remarkably little sound science guides the choice of drug.
- 83
- S. Diamond
- 1966
Medicine
JAMA
Patients with an acute skeletal-muscle spasm frequently pose a considerable problem to the practitioner who must deal with these spastic conditions and hence they seek medical attention for the purpose of shortening the acute phase of the disease.
- 17
- M. TulderTony TourayA. FurlanS. SolwayL. Bouter
- 2003
Medicine
The Cochrane database of systematic reviews
There is strong evidence that any of these muscle relaxants are more effective than placebo for patients with acute LBP on short-term pain relief, but the adverse effects require that they be used with caution.
- 238
- Highly Influential
- PDF
- D. BorensteinS. Korn
- 2003
Medicine
Clinical therapeutics
- 80
- Xu-ri LuoR. PietrobonL. CurtisL. Hey
- 2004
Medicine
- 16
- PDF
- D. BorensteinS. LacksS. Wiesel
- 1990
Medicine
Clinical therapeutics
It is demonstrated that patients with muscle spasm associated with acute low back strain benefited from the use of combination therapy consisting of a nonsteroidal anti-inflammatory agent (naproxen) and a muscle relaxant (cyclobenzaprine).
- 64
- J. Basmajian
- 1978
Medicine
Archives of physical medicine and rehabilitation
With improvement, myoelectric activity in back muscles is augmented during prescribed stressful movements as measured by electromyography and computer analysis combined with complex electrogoniometry.
- 45
- B. R. BrownJ. Womble
- 1978
Medicine
JAMA
The effectiveness of cyclobenzaprine hydrochloride, a new tricyclic skeletal muscle relaxant, was shown in patients with long-term intractable pain of cervical and lumbar origin aggravated by…
- 51
- R. BrowningJ. JacksonPatrick G. O’Malley
- 2001
Medicine
Archives of internal medicine
Cyclobenzaprine is more effective than placebo in the management of back pain; the effect is modest and comes at the price of greater adverse effects, suggesting that shorter courses may be better.
- 125
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